|Venue: AJ Bell Stadium Date: Friday, 15 October Kick-off: 19:45 BST Protection: Updates on BBC native radio and reside scores on the BBC Sport web site|
Sale’s British and Irish Lions flanker Tom Curry and England centre Manu Tuilagi return as they host Harlequins.
Tuilagi has missed the final two video games whereas Curry performs for the primary time this season as Sale make seven modifications.
Fly-half Marcus Smith is certainly one of three modifications champions Quins make from the aspect which got here again from 21-0 right down to beat Bristol final Friday.
Flanker James Chisholm replaces Tom Lawday whereas Luke Northmore comes into the backs instead of Louis Lynagh.
Smith replaces the injured Tomasso Allan having impressed final week’s dramatic turnaround after coming off the bench in his first look because the Lions tour, whereas two-try Lynagh is among the many replacements.
Sale give a begin to Bevan Rodd at loosehead after his call-up to the England coaching squad whereas Nick Schonert is available in at tighthead.
Cobus Wiese returns to the second row instead of JP du Preez whereas Jono Ross returns to the again row alongside Curry whereas Byron McGuigan begins on the wing forward of Arron Reed.
Sale: Hammersley; Solomona, S James, Tuilagi, McGuigan; Wilkinson, Quirke; Rodd, Langdon, Schonert, Wiese, JL du Preez, Ross (capt), T Curry, D du Preez.
Replacements: Taylor, Harrison, Oosthuizen, JP du Preez, Nield, Warr, Curtis, L James.
Harlequins: Inexperienced; Marchant, Northmore, Esterhuizen, Murley; Smith, Care; Marler, Walker, Kerrod, Symons, Lamb, Chisholm, Kenningham, Dombrandt (capt).
Replacements: Riley, Baxter, Collier, Tizard, Lawday, Steele, Jones, Lynagh.
Referee: Tom Foley (RFU).